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MEL-18 manages ESR1 transcription by the inhibiting the newest SUMOylation of the ESR1 transcription things p53 and you may SP1 (A) Cell lysates treated with 20 mM N-ethylmaleimide (NEM) were subjected to immunoblotting. The amount of SUMOylated protein was quantified by measuring the ratio of SUMOylated protein/total protein. (B) Venn diagram showing the relationship between…

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